PRKAA2, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of PRKAA2.

Supplier:  Abnova Corporation PAB19014

Catalog No. 89-120-567

Description

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and noncatalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq

Sequence: CPLDALNTTKP

Specifications

• Antigen: PRKAA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:16000) Sandwhich ELISA (1.5-3 ug/mL) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: PRKAA2
• Gene Symbols: PRKAA2
• Immunogen: A synthetic peptide corresponding to internal region of human PRKAA2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of PRKAA2.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: AMPK/AMPK2/PRKAA
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 5563
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only