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PTGS1 Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No. 89132139 Shop All Abnova Corporation Products
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89-132-139 100 μg
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Catalog No. 89-132-139 Supplier Abnova Corporation Supplier No. PAB6095
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Goat polyclonal antibody raised against synthetic peptide of PTGS1.

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq

Sequence: C-QDDGPAVERPSTEL

Specifications

Antigen PTGS1
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of PTGS1.
Dilution ELISA (1:32000) Western blot (1-3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene PTGS1
Gene Alias COX1/COX3/PCOX1/PGG/HS/PGHS-1/PGHS1/PHS1/PTGHS
Gene Symbols PTGS1
Host Species Goat
Immunogen A synthetic peptide corresponding to human PTGS1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5742
Test Specificity This antibody is expected to recognize both human isoforms of this protein according to NP_000953.2 and NP_542158.1.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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