RAB8A, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-399	100 μg

Catalog No. 89-133-399 Supplier Abnova Corporation Supplier No. PAB7594

Description

Goat polyclonal antibody raised against synthetic peptide of RAB8A.

The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800kb distal to MY09B on chromosome 19p13.1. [provided by RefSeq

Sequence: C-NQGVKITPDQQKR

Specifications

• Antigen: RAB8A
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of RAB8A.
• Dilution: ELISA (1:32000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: RAB8A
• Gene Alias: MEL/RAB8
• Gene Symbols: RAB8A
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human RAB8A.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4218
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only