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Description
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1; MIM 602048), and CDC42 (MIM 116952). GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM
Specifications
Specifications
| Antigen | RACGAP1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of RACGAP1. |
| Dilution | ELISA (1:32000) Western Blot (1-3 ug/mL)) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | RACGAP1 |
| Gene Alias | HsCYK-4/ID-GAP/MgcRacGAP |
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