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RAD51C, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89132284 Shop All Abnova Corporation Products
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100 μg
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89-132-284 100 μg
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Catalog No. 89-132-284 Supplier Abnova Corporation Supplier No. PAB6271
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Goat polyclonal antibody raised against synthetic peptide of RAD51C.

This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq

Sequence: RGKTFRFEMQRDL-C

Specifications

Antigen RAD51C
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of RAD51C.
Dilution ELISA (1:32000) Western blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene RAD51C
Gene Alias MGC104277/RAD51L2
Gene Symbols RAD51C
Host Species Goat
Immunogen A synthetic peptide corresponding to human RAD51C.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5889
Test Specificity This antibody is expected to recognize all three human isoforms.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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