RANGAP1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-503	100 μg

Catalog No. 89-132-503 Supplier Abnova Corporation Supplier No. PAB6571

Description

Goat polyclonal antibody raised against synthetic peptide of RANGAP1.

RanGAP1, is a homodimeric 65kDa polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq

Sequence: ASEDIAKLAETLAK-C

Specifications

• Antigen: RANGAP1
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of RANGAP1.
• Dilution: ELISA (1:32000) Western blot (0.1-0.5 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: RANGAP1
• Gene Alias: Fug1/KIAA1835/MGC20266/SD
• Gene Symbols: RANGAP1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human RANGAP1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5905
• Test Specificity: In mouse, there is a hypothetical protein called “similar to RANGAP1” (XP_139737.2) that is virtually identical.
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only