RFX5, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-129-122	100 μg

Catalog No. 89-129-122 Supplier Abnova Corporation Supplier No. PAB27612

Description

Goat polyclonal antibody raised against synthetic peptide of RFX5.

A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75kDa subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq

Sequence: TGDKSSEPSTLSNE

Specifications

• Antigen: RFX5
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of RFX5.
• Dilution: ELISA (1:1000) Western Blot (1-3ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: RFX5
• Gene Symbols: RFX5
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human RFX5.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5993
• Target Species: Canine, Chicken, Human, Mouse, Pig, Rabbit, Rat
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only