RPE65, Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of RPE65.
Supplier: Abnova Corporation PAB7451
This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeqSequence: C-EVKKNARKAPQPE
|ELISA (1:32000) Western Blot (0.5-1.5 ug/mL) The optimal working dilution should be determined by the end user.
|A synthetic peptide corresponding to human RPE65.
|ELISA, Western Blot
|Goat polyclonal antibody raised against synthetic peptide of RPE65.
|In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
|Antigen affinity purification
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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