RPE65, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-133-264	100 μg

Catalog No. 89-133-264 Supplier Abnova Corporation Supplier No. PAB7451

Description

Goat polyclonal antibody raised against synthetic peptide of RPE65.

This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq

Sequence: C-EVKKNARKAPQPE

Specifications

• Antigen: RPE65
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of RPE65.
• Dilution: ELISA (1:32000) Western Blot (0.5-1.5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: RPE65
• Gene Alias: LCA2/RP20/mRPE65/rd12/sRPE65
• Gene Symbols: RPE65
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human RPE65.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6121
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only