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RPE65, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of RPE65.

Supplier:  Abnova Corporation PAB7451

Catalog No. 89-133-264


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Description

Description

This gene encodes a protein which is located in the retinal pigment epithelium and is involved in the production of 11-cis retinal and in visual pigment regeneration. There are two forms of this protein, a soluble form called sRPE65, and a palmitoylated, membrane-bound form known as mRPE65. mRPE65 serves as the palmitoyl donor for lecithin retinol acyl transferase (LRAT), the enzyme that catalyzes the vitamin A to all trans retinol step of the chromophore regeneration process. Both mRPE65 and sRPE65 also serve as regulatory proteins, with the ratio and concentrations of these molecules playing a role in the inhibition of 11-cis retinal synthesis. Mutations in this gene have been associated with Leber congenital amaurosis type 2 (LCA2) and retinitis pigmentosa. [provided by RefSeq

Sequence: C-EVKKNARKAPQPE
Specifications

Specifications

RPE65
Polyclonal
Unconjugated
ELISA (1:32000) Western Blot (0.5-1.5 ug/mL) The optimal working dilution should be determined by the end user.
RPE65
RPE65
A synthetic peptide corresponding to human RPE65.
100 μg
Primary
Human
Liquid
ELISA, Western Blot
0.5 mg/mL
Goat polyclonal antibody raised against synthetic peptide of RPE65.
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
LCA2/RP20/mRPE65/rd12/sRPE65
Goat
Antigen affinity purification
RUO
6121
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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