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SART1, Goat, Polyclonal Antibody, Abnova™

Catalog No. 89132307 Shop All Abnova Corporation Products
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89-132-307 100 μg
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Catalog No. 89-132-307 Supplier Abnova Corporation Supplier No. PAB6298
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Goat polyclonal antibody raised against synthetic peptide of SART1.

This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq

Sequence: GSSKKHRGEKEAA-C

Specifications

Antigen SART1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of SART1.
Dilution ELISA (1:64000) Western Blot (0.03-0.1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene SART1
Gene Alias Ara1/HOMS1/MGC2038/SART1259/SNRNP110/Snu66
Gene Symbols SART1
Host Species Goat
Immunogen A synthetic peptide corresponding to human SART1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9092
Test Specificity This antibody is expected to recognize both the human SART1(259) and SART1(800) proteins.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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For Research Use Only

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