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Description
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq
Specifications
Specifications
| Antigen | SEPT6. |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of SEPT6. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(3-5 ug/mL) ELISA (1:4000) Western Blot (0.03-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | SEPT6 |
| Gene Alias | KIAA0128/MGC16619/MGC20339/SEP2/SEPT2 |
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