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Description
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq
Specifications
Specifications
| Antigen | SFRP1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of SFRP1. |
| Dilution | ELISA (1:1000) Immunohistochemistry (3-6 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 0.5mg/mL in Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | SFRP1 |
| Gene Alias | FRP/FRP-1/FRP1/FrzA/SARP2 |
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