SH2D1A Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of SH2D1A.

Supplier:  Abnova Corporation PAB6907

Catalog No. 89-132-788

Description

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-QYPVEKKSSARSTQ

Specifications

• Antigen: SH2D1A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:32000) Western Blot (0.2-0.6 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: SH2D1A
• Gene Symbols: SH2D1A
• Immunogen: A synthetic peptide corresponding to human SH2D1A.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of SH2D1A.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: DSHP/EBVS/FLJ18687/FLJ92177/IMD5/LYP/MTCP1/SAP/XLP/XLPD
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 4068
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

For Research Use Only