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SH2D1A Goat anti-Human, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of SH2D1A.
Supplier: Abnova Corporation PAB6907
Description
This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Sequence: C-QYPVEKKSSARSTQSpecifications
SH2D1A | |
Polyclonal | |
Unconjugated | |
ELISA (1:32000) Western Blot (0.2-0.6 ug/mL) The optimal working dilution should be determined by the end user. | |
SH2D1A | |
SH2D1A | |
A synthetic peptide corresponding to human SH2D1A. | |
100 μg | |
Primary | |
Human | |
Liquid |
ELISA, Western Blot | |
0.5 mg/mL | |
Goat polyclonal antibody raised against synthetic peptide of SH2D1A. | |
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) | |
DSHP/EBVS/FLJ18687/FLJ92177/IMD5/LYP/MTCP1/SAP/XLP/XLPD | |
Goat | |
Antigen affinity purification | |
RUO | |
4068 | |
Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
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