SIRT1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-121-189	100 μg

Catalog No. 89-121-189 Supplier Abnova Corporation Supplier No. PAB19664

Description

Goat polyclonal antibody raised against synthetic peptide of SIRT1.

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Sequence: C-EKPQEVQTSRNVES

Specifications

• Antigen: SIRT1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of SIRT1.
• Dilution: ELISA (1:64000) Western Blot (0.05-0.2 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: SIRT1
• Gene Alias: SIR2L1
• Gene Symbols: SIRT1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to amino acids 577-590 at internal region of human SIRT1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23411
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_036370.2; NP_001135970.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only