SIRT3 Goat anti-Human, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of SIRT3.

Supplier:  Abnova Corporation PAB6891

Catalog No. 89-132-774

Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq

Sequence: C-QRETGKLDGPDK

Specifications

• Antigen: SIRT3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:128000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: SIRT3
• Gene Symbols: SIRT3
• Immunogen: A synthetic peptide corresponding to human SIRT3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_036371.1 and NP_001017524.1).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of SIRT3.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: SIR2L3
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 23410
• Target Species: Human
• Form: Liquid

For Research Use Only