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Description
Glutamate and aspartate are excitatory neurotransmitters that have been implicated in a number of pathologic states of the nervous system. Accumulation of extracellular excitatory amino acids can be cytotoxic and may also lower the seizure threshold in epilepsy. EAAT1 (SLC1A3) is a member of a family of high-affinity sodium-dependent transporter molecules that regulate neurotransmitter concentrations at the excitatory glutamatergic synapses of the mammalian central nervous system (Kirschner et al., 1994 [PubMed 8001975]).[supplied by OMIM
Specifications
Specifications
| Antigen | SLC1A3 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of SLC1A3. |
| Dilution | ELISA (1:128000) Western Blot (0.1-0.3ug/ml) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA) |
| Gene | SLC1A3 |
| Gene Alias | EA6/EAAT1/FLJ25094/GLAST/GLAST1 |
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