SLC46A1, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of SLC46A1.

Supplier:  Abnova Corporation PAB19698

Catalog No. 89-121-225

Description

This gene encodes a transmembrane proton-coupled folate transporter protein that facilitates the movement of folate and antifolate substrates across cell membranes optimally in acidic pH environments. This protein is also expressed in the brain and choroid plexus where it transports folates into the central nervous system. This protein further functions as a transmembrane heme transporter in duodenal enterocytes and, potentially, in other tissues like liver and kidney. Its localization to the apical membrane or cytoplasm of intestinal cells is modulated by dietary iron levels. Mutations in this gene cause the autosomal recessive hereditary folate malabsorption (HFM) disease. HFM is characterized by folate deficiency due to reduced intestinal folate absorption and subsequent anemia, hypoimmunoglobulinemia, and recurrent infections. [provided by RefSeq

Sequence: C-LKEPKSTRLFTFRH

Specifications

• Antigen: SLC46A1
• Classification: Polyclonal
• Description: Goat polyclonal antibody raised against synthetic peptide of SLC46A1.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: HCP1/MGC9564/PCFT
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 113235
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: SLC46A1
• Gene Symbols: SLC46A1
• Immunogen: A synthetic peptide corresponding to amino acids 233-247 at internal region of human SLC46A1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only