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Description
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
Specifications
Specifications
| Antigen | SLC6A4 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of SLC6A4. |
| Dilution | ELISA (1:32000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA) |
| Gene | SLC6A4 |
| Gene Alias | 5-HTT/5HTT/HTT/OCD1/SERT/hSERT |
| Gene Symbols | SLC6A4 |
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