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Description
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq
Specifications
Specifications
| Antigen | SNX1 |
| Applications | ELISA, Immunohistochemistry (PFA fixed), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of SNX1. |
| Dilution | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(3-5 ug/mL) ELISA (1:16000) Western Blot (0.05-0.1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA) |
| Gene | SNX1 |
| Gene Alias | HsT17379/MGC8664/SNX1A/Vps5 |
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