SOCS1, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-060	100 μg

Catalog No. 89-132-060 Supplier Abnova Corporation Supplier No. PAB6012

Description

Goat polyclonal antibody raised against synthetic peptide of SOCS1.

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq

Sequence: C-VLRDYLSSFPFQI

Specifications

• Antigen: SOCS1
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of SOCS1.
• Dilution: ELISA (1:4000) Western blot (1-3 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: SOCS1
• Gene Alias: CIS1/CISH1/JAB/SOCS-1/SSI-1/SSI1/TIP3
• Gene Symbols: SOCS1
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to C terminus of human SOCS1.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8651
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only