TIRAP Goat anti-Human, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-132-775	100 μg

Catalog No. 89-132-775 Supplier Abnova Corporation Supplier No. PAB6892

Description

Goat polyclonal antibody raised against synthetic peptide of TIRAP.

The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq

Sequence: C-QTLLKKPKKRPNSPE

Specifications

• Antigen: TIRAP
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of TIRAP.
• Dilution: ELISA (1:32000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene: TIRAP
• Gene Alias: FLJ42305/Mal/wyatt
• Gene Symbols: TIRAP
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to human TIRAP.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 114609
• Test Specificity: This antibody is expected to recognize both reported isoforms (NP_001034750.1 and NP_683708.1).
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only