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Description
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | TRIM24 |
| Applications | ELISA, Immunohistochemistry (PFA fixed) |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Description | Goat polyclonal antibody raised against synthetic peptide of TRIM24. |
| Dilution | ELISA (1:32000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide) |
| Gene | TRIM24 |
| Gene Alias | PTC6/RNF82/TF1A/TIF1/TIF1A/TIF1ALPHA/hTIF1 |
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