WT1, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of WT1.

Supplier:  Abnova Corporation PAB7070

Catalog No. 89-132-926

Description

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq]

Sequence: QDPASTCVPEPASQH

Specifications

• Antigen: WT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:4000) Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: WT1
• Gene Symbols: WT1
• Immunogen: A synthetic peptide corresponding to human WT1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody is expected to recognize all four reported isoforms (NP_000369.3, NP_077742.2, NP_077743.2, NP_077744.3).
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of WT1.
• Formulation: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
• Gene Alias: GUD/WAGR/WIT-2/WT33
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7490
• Target Species: Human
• Form: Liquid

For Research Use Only