ZAP70, Goat, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-126-322	100 μg

Catalog No. 89-126-322 Supplier Abnova Corporation Supplier No. PAB24606

Description

Goat polyclonal antibody raised against synthetic peptide of ZAP70.

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq

Sequence: C-SDGYTPEPARITSPD

Specifications

• Antigen: ZAP70
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Goat polyclonal antibody raised against synthetic peptide of ZAP70.
• Dilution: ELISA (1:32000) Western Blot (0.3-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In 0.5mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene: ZAP70
• Gene Alias: FLJ17670/FLJ17679/SRK/STD/TZK/ZAP-70
• Gene Symbols: ZAP70
• Host Species: Goat
• Immunogen: A synthetic peptide corresponding to internal region of human ZAP70.
• Purification Method: Antigen affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7535
• Test Specificity: This antibody is expected to recognize isoform 1 (NP_001070.2) only.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid

For Research Use Only