Golgin-97 Mouse anti-Human, Clone: CDF4, eBioscience™ Invitrogen™
Mouse Monoclonal Antibody
The monoclonal antibody CDF4 recognizes human Golgin-97. Golgin-97, a GRIP domain protein member that was first identified as a Golgi complex autoantigen associated with Sjogren's syndrome. Golgin-97 is a peripheral membrane protein found on the trans face of the Golgi apparatus. The protein G family member, Arl1, mediates the binding of Golgin-97 to the Golgi membrane. Like all GRIP proteins, Golgin-97 functions in maintaining the integrity of the trans Golgi network. Golgin-97 has also been shown to function as a tethering molecule in the retrograde transport of proteins from the endosomes to the trans Golgi network. During poxvirus infection, Golgin-97 incorporates into virions and plays a role in viral replication and morphogenesis. Applications Reported: This CDF4 antibody has been reported for use in western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, immunohistochemical staining, and immunocytochemistry. Applications Tested: This CDF4 antibody has been tested by immunocytochemistry of fixed and permeabilized HeLa cells and can be used at less than or equal to 1 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.Golgin-97 Monoclonal antibody specifically detects Golgin-97 in Human samples. It is validated for Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|0710001G09Rik; 2210418B03Rik; AW107649; gap junction protein, alpha 4, 37kD; Golga1; golgi autoantigen, golgin subfamily a, 1; Golgi97; golgin A1; Golgin subfamily A member 1; Golgin-97|
|PBS with 0.09% sodium azide; pH 7.2|
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