Invitrogen™ GORAB Monoclonal Antibody (OTI1E3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526042

Catalog No. PIMA526042

Description

GORAB Monoclonal Antibody for Western Blot, IHC (P)

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.

Specifications

• Antigen: GORAB
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: B1H222, Q5T7V8, Q8BRM2
• Gene Symbols: Gorab
• Immunogen: Human recombinant protein fragment corresponding to amino acids 35-394 of GORAB produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1E3
• Conjugate: Unconjugated
• Gene: Gorab
• Gene Alias: AI467484; dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued; GO; golgin, RAB6 interacting; golgin, RAB6-interacting; Gorab; hNTKL-BP1; mNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKLBP1; NTKL-BP1; RAB6-interacting golgin; RAB6-interacting golgin-like protein; SCY1-like 1 binding protein 1; SCY1-like 1-binding protein 1; SCYL1-binding protein 1; Scyl1bp1; SCYL1-BP1
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 304923, 490349, 92344, 98376
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid