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Invitrogen™ GORAB Monoclonal Antibody (OTI1E3)
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Catalog No. PIMA526042
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100 μL
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PIMA526042 100 μL
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Catalog No. PIMA526042 Supplier Invitrogen™ Supplier No. MA526042
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Description

Mouse Monoclonal Antibody

GORAB Monoclonal Antibody for Western Blot, IHC (P)

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GORAB
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1E3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Gorab
Gene Accession No. B1H222, Q5T7V8, Q8BRM2
Gene Alias AI467484; dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued; GO; golgin, RAB6 interacting; golgin, RAB6-interacting; Gorab; hNTKL-BP1; mNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKLBP1; NTKL-BP1; RAB6-interacting golgin; RAB6-interacting golgin-like protein; SCY1-like 1 binding protein 1; SCY1-like 1-binding protein 1; SCYL1-binding protein 1; Scyl1bp1; SCYL1-BP1
Gene Symbols Gorab
Host Species Mouse
Immunogen Human recombinant protein fragment corresponding to amino acids 35-394 of GORAB produced in E.coli.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 304923, 490349, 92344, 98376
Target Species Human, Mouse, Rat, Canine, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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