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Invitrogen™ GORAB Polyclonal Antibody
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Catalog No. PIPA555543
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100 μL
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PIPA555543 100 μL
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Catalog No. PIPA555543 Supplier Invitrogen™ Supplier No. PA555543
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MSWAAVLAVA AARFGHFWGC RWPGPMAQGW AGFSEEELRR LKQTKDPFEP QRRLPAKKSR QQLQREKALV EQSQKLGLQD GSTSLLPEQL LSAP Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.

TCEB1 is known as protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Western blots using two different antibodies (P100962-T200 and P100963_P050 / P100963_P100) against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GORAB
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Gorab
Gene Accession No. Q5T7V8
Gene Alias AI467484; dynactin 1, isoform 1; dynactin 1 (p150, Glued homolog); p150, Glued homolog; 150 kDa dynein-associated polypeptide; p150-glued; GO; golgin, RAB6 interacting; golgin, RAB6-interacting; Gorab; hNTKL-BP1; mNTKL-BP1; N-terminal kinase-like-binding protein 1; NTKL-binding protein 1; NTKLBP1; NTKL-BP1; RAB6-interacting golgin; RAB6-interacting golgin-like protein; SCY1-like 1 binding protein 1; SCY1-like 1-binding protein 1; SCYL1-binding protein 1; Scyl1bp1; SCYL1-BP1
Gene Symbols Gorab
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GORAB. Recombinant protein control fragment (Product #RP-94149).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 92344
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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