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GP2 Antibody (GP2/1803) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP275781 Shop All R&D Systems Products
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100 μg
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NBP275781 100 μg
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Catalog No. NBP275781 Supplier Novus Biologicals Supplier No. NBP275781
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Description

Mouse Monoclonal Antibody

GP2 Monoclonal specifically detects GP2 in Human samples. It is validated for Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

Specifications

Antigen GP2
Applications ELISA, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone GP2/1803
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Formulation 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Accession No. P55259
Gene Alias DKFZp779K0533, glycoprotein 2 (zymogen granule membrane), pancreatic secretory granule membrane major glycoprotein GP2, pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
Gene Symbols GP2
Host Species Mouse
Immunogen Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary) (Uniprot: P55259)
Molecular Weight of Antigen 59 kDa
Purification Method Protein A or G purified
Quantity 100 μg
Primary or Secondary Primary
Gene ID (Entrez) 2813.0
Test Specificity GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Target Species Human
Content And Storage Store at 4°C.
Form Purified
Isotype IgG2a κ
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