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GP2 Mouse anti-Human, Clone: GP2/1803, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275781

Catalog No. NBP275781


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Description

Description

GP2 Monoclonal antibody specifically detects GP2 in Human samples. It is validated for ELISA, Immunohistochemistry (Paraffin).
Specifications

Specifications

GP2
GP2/1803
Unconjugated
10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Purified
GP2
Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
59 kDa
100 μg
Primary
2813.0
Human
ELISA, Immunohistochemistry (Paraffin)
0.2 mg/ml
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
P55259
DKFZp779K0533, glycoprotein 2 (zymogen granule membrane), pancreatic secretory granule membrane major glycoprotein GP2, pancreatic zymogen granule membrane associated protein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75
Mouse
IgG2a Kappa
Protein A or G purified
Store at 4°C.
Monoclonal
GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
SDS
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