gp96/HSP90B1/GRP94 Antibody (SPM249) - IHC-Prediluted, Novus Biologicals™

Rat Monoclonal Antibody

Supplier:  Novus Biologicals NBP248051

Catalog No. NBP248051

Description

gp96/HSP90B1/GRP94 Monoclonal specifically detects gp96/HSP90B1/GRP94 in Human, Mouse, Rat, Porcine, Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Monkey, Rabbit, Sheep, Xenopus samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: gp96/HSP90B1/GRP94
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: HSP90B1
• Immunogen: Purified glucose regulated protein 94 (grp94) from chicken oviducts (Uniprot: P14625)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This monoclonal antibody is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
• Content And Storage: Store at 4C.
• Isotype: IgG2a κ

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: SPM249
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: 94 kDa glucose-regulated protein, endothelial cell (HBMEC) glycoprotein, glucose regulated protein, 94 kDa, GP96ECGP, GRP-94, GRP94gp96 homolog, Heat shock protein 90 kDa beta member 1, heat shock protein 90kDa beta (Grp94), member 1, TRA1endoplasmin, tumor rejection antigen (gp96) 1, Tumor rejection antigen 1, Tumor rejection antigen-1 (gp96)
• Host Species: Rat
• Molecular Weight of Antigen: 94 kDa
• Quantity: 7 mL
• Research Discipline: Cancer, Cellular Markers, ER Markers, Golgi Apparatus Markers, Hypoxia, Membrane Trafficking and Chaperones
• Gene ID (Entrez): 7184
• Target Species: Human, Mouse, Rat, Pig, Canine, Chicken, Equine, Guinea Pig, Hamster, Primate, Monkey, Rabbit, Sheep, Xenopus species
• Form: Purified