GPAM Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-6310	100 μL

Catalog No. 50-198-6310 Supplier Bioss Supplier No. BS5063R

Description

Rabbit Polyclonal Antibody

Glycerol-3-phosphate acyltransferase 1 (GPAT1), one of four known GPAT isoforms, is located on the mitochondrial outer membrane, allowing reciprocal regulation with carnitine palmitoyltransferase-1. It is thought to be critical for the development of hepatic steatosis; steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance. GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase. Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets, suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. At least two isoforms of GPAT1 are known to exist.

Specifications

• Antigen: GPAM
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: Gpam
• Gene Accession No.: Q9HCL2
• Gene Alias: glycerol 3-phosphate acyltransferase, mitochondrial; Glycerol-3-phosphate acyltransferase 1, mitochondrial; glycerol-3-phosphate acyltransferase, mitochondrial; GPAM; GPAT; GPAT1; GPAT-1; KIAA1560; P90; RP11-426E5.2
• Gene Symbols: Gpam
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human GPAM.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57678
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG