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Invitrogen™ GPATCH3 Polyclonal Antibody

Catalog No. PIPA556918
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100 μL
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PIPA556918 100 μL
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Catalog No. PIPA556918 Supplier Invitrogen™ Supplier No. PA556918
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PNSALIPTDP AAEGQLLSQT SATDVRPLST RDSTPIQTRT CCCVISVRGL AQAQRLIRMY SGRRWLDSHG TWLPGRCLIR RLRLPTEASG LGSFPFKTRK EL Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 72%.

GPATCH3 is a protein coding gene involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPATCH3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GPATCH3
Gene Accession No. Q96I76
Gene Alias D930035B09Rik; G patch domain containing 3; G patch domain-containing protein 3; Gpatc3; G-patch domain containing 3; GPATCH3; RGD1311216
Gene Symbols GPATCH3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GPATCH3. Recombinant protein control fragment (Product #RP-94564).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 63906
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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