Invitrogen™ GPATCH3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556918

Catalog No. PIPA556918

Description

Immunogen sequence: PNSALIPTDP AAEGQLLSQT SATDVRPLST RDSTPIQTRT CCCVISVRGL AQAQRLIRMY SGRRWLDSHG TWLPGRCLIR RLRLPTEASG LGSFPFKTRK EL Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 72%.

GPATCH3 is a protein coding gene involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6.

Specifications

• Antigen: GPATCH3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPATCH3
• Gene Alias: D930035B09Rik; G patch domain containing 3; G patch domain-containing protein 3; Gpatc3; G-patch domain containing 3; GPATCH3; RGD1311216
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 63906
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96I76
• Gene Symbols: GPATCH3
• Immunogen: Recombinant protein corresponding to Human GPATCH3. Recombinant protein control fragment (Product #RP-94564).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG