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GPC3 Mouse anti-Human, Clone: SPM595, Abnova™

Catalog No. 89934205 Shop All Abnova Corporation Products
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89-934-205 100 μg
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Catalog No. 89-934-205 Supplier Abnova Corporation Supplier No. MAB13057
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Description

Mouse monoclonal antibody raised against partial recombinant human GPC3.

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Specifications

Antigen GPC3
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SPM595
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant human GPC3.
Dilution Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 1mM PBS.
Gene Alias DGSX/OCI-5/SDYS/SGB/SGBS/SGBS1
Gene Symbols GPC3
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 511-580 of human GPC3.
Purification Method Protein A/G purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2719
Target Species Human
Content And Storage Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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