GPC3 Mouse anti-Human, Clone: SPM595, Abnova™

Mouse monoclonal antibody raised against partial recombinant human GPC3.

Supplier:  Abnova Corporation MAB13057

Catalog No. 89-934-205

Description

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Specifications

• Antigen: GPC3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: DGSX/OCI-5/SDYS/SGB/SGBS/SGBS1
• Host Species: Mouse
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 2719
• Content And Storage: Store at -20 to -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Clone: SPM595
• Description: Mouse monoclonal antibody raised against partial recombinant human GPC3.
• Formulation: In 1mM PBS.
• Gene Symbols: GPC3
• Immunogen: Recombinant protein corresponding to amino acids 511-580 of human GPC3.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid