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GPCR C5L2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501983701
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50-198-3701 100 μL
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Catalog No. 50-198-3701 Supplier Bioss Supplier No. BS15352R
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Rabbit Polyclonal Antibody

C5AR2 is an orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.

Specifications

Antigen GPCR C5L2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene C5AR2
Gene Accession No. Q9P296
Gene Alias C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; C5AR2; C5L2; Complement component 5a receptor 2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; GPF77; GPR77; G-protein coupled receptor 77
Gene Symbols C5AR2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human GPCR C5L2 protein.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27202
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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