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Invitrogen™ GPCR/G-protein complex-stabilizing scFv Recombinant Mouse Monoclonal Antibody (scFv16)
Description
The scFv antibody stabilizes GPCR/G-protein complexes for cryo-EM of active structures. It recognizes an interface between G alpha and G beta/gamma subunits, and confers resistance to nucleotide exchange-triggered dissociation of the heterotrimeric G-protein. In addition to members of the Gi/o family, this antibody fragment can also be applied to chimeric variants and stabilize other G-protein subtypes including Gs complexes.
Specifications
Specifications
| Antigen | GPCR/G-protein complex-stabilizing scFv |
| Applications | Not Available |
| Classification | Recombinant Monoclonal |
| Clone | scFv16 |
| Concentration | 2.0 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 25mM HEPES with 10% glycerol and no preservative; pH 7.5 |
| Host Species | Mouse |
| Immunogen | Rhodopsin/Gi1. |
| Purification Method | Affinity chromatography |
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