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Invitrogen™ GPCR/G-protein complex-stabilizing scFv Recombinant Mouse Monoclonal Antibody (scFv16)
Mouse Recombinant Monoclonal Antibody
Supplier: Invitrogen™ 703976

Description
The scFv antibody stabilizes GPCR/G-protein complexes for cryo-EM of active structures. It recognizes an interface between G alpha and G beta/gamma subunits, and confers resistance to nucleotide exchange-triggered dissociation of the heterotrimeric G-protein. In addition to members of the Gi/o family, this antibody fragment can also be applied to chimeric variants and stabilize other G-protein subtypes including Gs complexes.

Specifications
GPCR/G-protein complex-stabilizing scFv | |
Recombinant Monoclonal | |
2.0 mg/mL | |
25mM HEPES with 10% glycerol and no preservative; pH 7.5 | |
Rhodopsin/Gi1. | |
100 μg | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Not Available | |
scFv16 | |
Unconjugated | |
Mouse | |
Affinity Chromatography | |
RUO | |
Human | |
Antibody |
Safety and Handling
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