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Invitrogen™ GPCR/G-protein complex-stabilizing scFv Recombinant Mouse Monoclonal Antibody (scFv16)
Mouse Recombinant Monoclonal Antibody
Supplier: Invitrogen™ 703976
Description
The scFv antibody stabilizes GPCR/G-protein complexes for cryo-EM of active structures. It recognizes an interface between G alpha and G beta/gamma subunits, and confers resistance to nucleotide exchange-triggered dissociation of the heterotrimeric G-protein. In addition to members of the Gi/o family, this antibody fragment can also be applied to chimeric variants and stabilize other G-protein subtypes including Gs complexes.
Specifications
| GPCR/G-protein complex-stabilizing scFv | |
| Recombinant Monoclonal | |
| 2.0 mg/mL | |
| 25mM HEPES with 10% glycerol and no preservative; pH 7.5 | |
| Rhodopsin/Gi1. | |
| 100 μg | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Not Available | |
| scFv16 | |
| Unconjugated | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| Human | |
| Antibody |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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