GPCR TGR5/GPBAR1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS8874R

Catalog No. 50-198-8732

Description

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: GPCR TGR5/GPBAR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPBAR1
• Gene Alias: BG37; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; GPBAR1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; hGPCR19; M-BAR; membrane bile acid receptor; Membrane-type receptor for bile acids; TGR5
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 151306
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q8TDU6
• Gene Symbols: GPBAR1
• Immunogen: KLH conjugated synthetic peptide derived from human GPBAR1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG