Invitrogen™ GPD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593093

Catalog No. PIPA593093

Description

Immunogen sequence: SQFAHYRRKQ MNLAYVKAAD CISEPVNREP PSREAQLLTL QNTSEFDILV IGGGATGSGC ALDAVTRGLK TALVERDDFS SGTSSRSTKL IHGGVRYLQK AIMKLDIEQY RMVKEALHER ANLLEIAPHL SAPLPIMLPV YKWWQLPYYW VGIKLYDLVA GSNCLKSSYV LSKSRALEHF PMLQKDKLVG AIVYYDGQHN DARMNLAIAL TAARYGAATA NYMEVVSLLK KTDPQTGKVR VSGARCKDVL TGQEFDVRAK CVINATGPFT DSVRKMDDKD AAAICQPSAG VHIVMPGYYS P; Positive Samples: MCF7, THP-1, SW480, Mouse skeletal muscle, Mouse liver, Mouse pancreas, Mouse brain; Cellular Location: Mitochondrion.

Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.

Specifications

• Antigen: GPD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gpd2
• Gene Alias: AA408484; AI448216; AU021455; AW494132; FAD-linked glycerol-3-phosphate dehydrogenase; GDH2; Gdm1; glycerol phosphate dehydrogenase 1, mitochondrial; glycerol phosphate dehydrogenase 2, mitochondrial; Glycerol-3-phosophate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2; glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2, mitochondrial; glycerol-3-phosphate dehydrogenase, mitochondrial; Gpd2; GPDH; GPDH-M; GPDM; GPD-M; mGPDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mtGPD; mtGPDH; mtGPDH gene, promoter region and alternative transcripts; Protein TISP38; testicular tissue protein Li 76; TISP38
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14571, 25062, 2820
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.86 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35571, P43304, Q64521
• Gene Symbols: Gpd2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-325 of human GPD2 (NP_0003993).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG