Invitrogen™ GPIHBP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589108

Catalog No. PIPA589108

Description

Immunogen sequence: ETNRLPGGRS RVLLRCYTCK SLPRDERCNL TQNCSHGQTC TTLIAHGNTE SGLLTTHSTW CTDSCQPITK TVEGTQVTMT CCQSSLCNVP PWQSSRVQDP TG; Positive Samples: U-87MG, LO2; Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Peripheral membrane protein.

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.

Specifications

• Antigen: GPIHBP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPIHBP1
• Gene Alias: 1110002J19Rik; endothelial cell LPL transporter; glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1; glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GPI anchored high density lipoprotein binding protein 1; GPI-anchored HDL-binding protein 1; Gpihbp1; GPI-HBP1; Hbp1; HDLBP; HDLBP1; High density lipoprotein-binding protein 1; HYPL1D; RGD1564237
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 338328
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.68 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8IV16
• Gene Symbols: GPIHBP1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-151 of human GPIHBP1 (NP_8354662).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG