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Invitrogen™ GPIHBP1 Polyclonal Antibody
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Catalog No. PIPA589108
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100 μL
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PIPA589108 100 μL
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Catalog No. PIPA589108 Supplier Invitrogen™ Supplier No. PA589108
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETNRLPGGRS RVLLRCYTCK SLPRDERCNL TQNCSHGQTC TTLIAHGNTE SGLLTTHSTW CTDSCQPITK TVEGTQVTMT CCQSSLCNVP PWQSSRVQDP TG; Positive Samples: U-87MG, LO2; Cellular Location: Apical cell membrane, Basolateral cell membrane, Cell membrane, Extracellular side, GPI-anchor, Lipid-anchor, Peripheral membrane protein.

GPI-anchored HDL-binding protein 1 (Gpihbp1) is a novel protein that may be involved in the regulation of the delivery of fats to cells for energy and storage. Digested fats travel to the small intestine, where they are packaged into chylomicrons (particles filled with triglycerides). Chylomicrons then travel through the bloodstream and deliver triglycerides to tissues that are hungry for fuel or to adipose tissue for energy storage. Triglycerides are broken down or hydrolyzed by the enzyme lipoprotein lipase (LpL). The triglyceride breakdown products are then taken up and used by cells. Gpihbp1 is the molecule in capillaries that facilitates the capture of chylomicrons and facilitates the interaction with LpL. It has been shown that fats in the bloodstream are not readily metabolized in the absence of GPIHBP1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPIHBP1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene GPIHBP1
Gene Accession No. Q8IV16
Gene Alias 1110002J19Rik; endothelial cell LPL transporter; glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1; glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GPI anchored high density lipoprotein binding protein 1; GPI-anchored HDL-binding protein 1; Gpihbp1; GPI-HBP1; Hbp1; HDLBP; HDLBP1; High density lipoprotein-binding protein 1; HYPL1D; RGD1564237
Gene Symbols GPIHBP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 50-151 of human GPIHBP1 (NP_8354662).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 338328
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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