Invitrogen™ GPIP137 Recombinant Rabbit Monoclonal Antibody (6H17L10)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703658

Catalog No. 70-365-8

Description

This antibody is predicted to react with Monkey, Pig, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types. It binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, mRNAs, GRIN1, and KPNB1 mRNAs.

Specifications

• Antigen: GPIP137
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q14444
• Gene Symbols: Caprin1
• Immunogen: Protein corresponding to human GPIP137 [aa132-aa251].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: RNA Immunoprecipitation, Immunocytochemistry
• Clone: 6H17L10
• Conjugate: Unconjugated
• Gene: Caprin1
• Gene Alias: activation/proliferation-associated protein 1; AL022980; caprin 1; Caprin1; caprin-1; cell cycle associated protein 1; cell cycle-associated protein 1; cytop; Cytoplasmic activation- and proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein 1; cytoplasmic activation/proliferation-associated protein-1; G5E5; GPI p137; GPI-anchored membrane protein 1; GPI-anchored protein p137; Gpiap; GPIAP1; Gpip137; GPI-p137; GRIP137; M11S1; Membrane component chromosome 11 surface marker 1; membrane component, chromosome 11, surface marker 1; Mmgpip137; P137; p137GPI; RNA granule protein 105; Rng105
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4076
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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