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Invitrogen™ GPM6A Polyclonal Antibody
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Catalog No. PIPA5142638
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100 μg
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PIPA5142638 100 μg
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Catalog No. PIPA5142638 Supplier Invitrogen™ Supplier No. PA5142638
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Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize all reported isoforms (NP_005268.1; NP_963885.1; NP_963886.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000. This antibody is not recommended for ICC/IF.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPM6A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GPM6A
Gene Accession No. P35802, P51674, Q812E9
Gene Alias glycoprotein m6a; GPM6; Gpm6a; M6A; neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a-like
Gene Symbols GPM6A
Host Species Goat
Immunogen Peptide with sequence C-QTYFEMARTAGD.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234267, 2823, 306439
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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