Invitrogen™ GPM6A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550350

Catalog No. PA550350

Description

The antibody detects endogenous levels of total GPM6A protein.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Specifications

• Antigen: GPM6A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPM6A
• Gene Alias: glycoprotein m6a; GPM6; Gpm6a; M6A; neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a-like
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 234267, 2823, 306439
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.9 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P35802, P51674, Q812E9
• Gene Symbols: GPM6A
• Immunogen: Fusion protein corresponding to a region derived from internal residues of human glycoprotein M6A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG