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Invitrogen™ GPM6A Polyclonal Antibody
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Catalog No. PIPA553588
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100 μL
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Catalog No. Quantity
PIPA553588 100 μL
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Catalog No. PIPA553588 Supplier Invitrogen™ Supplier No. PA553588
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YFNLWTICRN TTLVEGANLC LDLRQFGIVT IGEEKKICTV SENFLRMCES TELN Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.

Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPM6A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GPM6A
Gene Accession No. P51674
Gene Alias glycoprotein m6a; GPM6; Gpm6a; M6A; neuronal membrane glycoprotein M6-a; neuronal membrane glycoprotein M6-a-like
Gene Symbols GPM6A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GPM6A. Recombinant protein control fragment (Product #RP-91159).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2823
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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