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Invitrogen™ GPNMB Monoclonal Antibody (303822)
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Catalog No. PIMA524014
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100 μg
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Catalog No. Quantity
PIMA524014 100 μg
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Catalog No. PIMA524014 Supplier Invitrogen™ Supplier No. MA524014
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Description

Mouse Monoclonal Antibody

In direct ELISAs, no cross-reactivity with recombinant mouse Osteoactivin is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPNMB
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 303822
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene GPNMB
Gene Accession No. Q14956
Gene Alias Dchil; DC-HIL; dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand; dendritic cell-associated transmembrane protein; glycoprotein (transmembrane) nmb; glycoprotein nmb; glycoprotein nmb-like protein; glycoprotein nonmetastatic melanoma protein B; Gpnmb; hematopoietic growth factor inducible neurokinin-1; Hematopoietic growth factor inducible neurokinin-1 type; Hgfin; ipd; iris pigment dispersion; NMB; Osteoactivin; si:ch211-155k24.6; transmembrane glycoprotein HGFIN; transmembrane glycoprotein NMB; Unknown (protein for MGC:133733); UNQ1725/PRO9925
Gene Symbols GPNMB
Host Species Mouse
Immunogen Mouse myeloma cell line NS0-derived recombinant human Osteoactivin/GPNMBisoform 2 Ala22-Asn486.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10457
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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