Invitrogen™ GPR110 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575346

Catalog No. PIPA575346

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR110 (G protein-coupled receptor 110), also known as PGR19, is a 911 amino acid protein that belongs to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Characterized as an adhesion GPCR, GPR110 is a multipass membrane-bound protein with a long amino-terminus that contains multiple domains. One of these domains is the GPCR proteolytic site (GPS), which is essential for proteolytic cleavage of the amino-terminus and for cell surface expression.

Specifications

• Antigen: GPR110
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRF1
• Gene Alias: 5031409J19Rik; Adgrf1; adhesion G protein-coupled receptor F1; adhesion G-protein coupled receptor F1; G protein-coupled receptor 110; G protein-coupled receptor KPG_012; G protein-coupled receptor PGR19; Gpr110; G-protein coupled receptor 110; G-protein coupled receptor KPG_012; hGPCR36; internal gene name of KIRIN laboratory:M5; KPG_009; KPG_012; PGR19; probable G-protein coupled receptor 110; seven transmembrane helix receptor
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 266977, 301266, 77596
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.2
• Gene Accession No.: Q5T601, Q8VEC3
• Gene Symbols: ADGRF1
• Immunogen: Synthetic peptide corresponding to amino acids 846-898 of Human GPR110.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG