Invitrogen™ GPR112 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599890

Catalog No. PIPA599890

Description

Antibody detects endogenous levels of total GPR112.

G protein-coupled receptors(GPRs or GPCRs), also known asseven transmembrane receptors, heptahelical receptors or 7TMreceptors, aremembers of the largest protein family and play a role in many differentstimulus-response pathways. G protein-coupled receptors mediate extracellularsignals into intracellularsignals(G protein activation). Theyrespond to awide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usuallyintegralseven passmembrane proteins with some conserved amino acid regions. GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein that belongsto the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localizing to cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, aswell as neuroendocrine and primarylivercarcinoma. GPR112 contains one GPS domain andmayfunction as an orphan receptor.

Specifications

• Antigen: GPR112
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRG4
• Gene Alias: ADGRG4; adhesion G protein-coupled receptor G4; adhesion G-protein coupled receptor G4; G protein-coupled receptor 112; Gm367; GPR112; G-protein coupled receptor 112; PGR17; probable G-protein coupled receptor 112; RP1-299I16
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 139378
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8IZF6
• Gene Symbols: ADGRG4
• Immunogen: A synthesized peptide derived from human ADGRG4(Accession Q8IZF6), corresponding to amino acid residues T3047-P3080.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov