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Invitrogen™ GPR112 Polyclonal Antibody
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Catalog No. PIPA537269
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100 μL
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PIPA537269 100 μL
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Catalog No. PIPA537269 Supplier Invitrogen™ Supplier No. PA537269
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 333 kDa. Purity is >95% by SDS-PAGE.

G protein-coupled receptors(GPRs or GPCRs), also known asseven transmembrane receptors, heptahelical receptors or 7TMreceptors, aremembers of the largest protein family and play a role in many differentstimulus-response pathways. G protein-coupled receptors mediate extracellularsignals into intracellularsignals(G protein activation). Theyrespond to awide variety of signaling molecules, including hormones, neurotransmitters and other proteins and peptides. GPR proteins are usuallyintegralseven passmembrane proteins with some conserved amino acid regions. GPR112 (G protein-coupled receptor 112) is a 3,080 amino acid multi-pass membrane protein that belongsto the G-protein coupled receptor 2 family and LN-TM7 subfamily. Localizing to cell membrane, GPR112 is highly expressed in normal enterochromaffin cells, aswell as neuroendocrine and primarylivercarcinoma. GPR112 contains one GPS domain andmayfunction as an orphan receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR112
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ADGRG4
Gene Accession No. B7ZCC9, Q8IZF6
Gene Alias ADGRG4; adhesion G protein-coupled receptor G4; adhesion G-protein coupled receptor G4; G protein-coupled receptor 112; Gm367; GPR112; G-protein coupled receptor 112; PGR17; probable G-protein coupled receptor 112; RP1-299I16
Gene Symbols ADGRG4
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human GPR112.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 139378, 236798
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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