Invitrogen™ GPR116 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533612

Catalog No. PIPA533612

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (90%). For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR116 (G protein-coupled receptor 116) is a 1,346 amino acid multi-pass membrane protein that contains one SEA domain, one GPS domain and three Ig-like domains and belongs to the GPR family. Existing as a dilsulfide-liked homodimer at the cell surface, GPR116 exists as multiple alternatively spliced isoforms and is thought to play a role in regulating and maintaining proper acid-base balance throughout the cell.

Specifications

• Antigen: GPR116
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ADGRF5
• Gene Alias: 8430401C09Rik; 9330185D23; ADGRF5; Adhesion G protein-coupled receptor F5; AI528491; DKFZp564O1923; FLJ90640; G protein-coupled hepta-helical receptor Ig-Hepta; G protein-coupled receptor 116; Gpr116; Gprhep; G-protein coupled hepta-helical receptor Ig-hepta; G-protein coupled receptor 116; Ig-Hepta; Ig-Hepta homolog; KIAA0758; KPG_001; mKIAA0758; probable G-protein coupled receptor 116
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 221395
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q8IZF2
• Gene Symbols: ADGRF5
• Immunogen: Synthetic 20 amino acid peptide from internal region of human GPR116.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov