Invitrogen™ GPR12 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532793

Catalog No. PIPA532793

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Hamster, Panda, Horse, Pig, Opossum (100%); Bat, Elephant, Rabbit (94%); Turkey, Chicken (88%); Platypus, Xenopus (81%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR12 is an orphan G-protein-coupled receptor which constitutively activates the Gs protein and increases intracellular cAMP. GPR12 can also be activated by sphingosylphosphorylcholine to promote various cellular functions which include proliferation, neurite outgrowth, cell survival and differentiation.

Specifications

• Antigen: GPR12
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR12
• Gene Alias: FLJ18149; FLJ97704; G protein-coupled receptor 12; GPCR01; GPCR12; Gpcr20; Gpcr21; Gpr12; G-protein coupled receptor 12; MGC138349; MGC138351; PPP1R84; protein phosphatase 1, regulatory subunit 84; R334
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100050970, 100736641, 100764513, 14738, 2835, 486034, 522747, 80840
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.8 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P30951, P35412, P47775
• Gene Symbols: GPR12
• Immunogen: Synthetic 16 amino acid peptide from 1st extracellular domain of human GPR12 / GPCR12.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey, Bovine, Hamster, Pig, Horse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov