GPR124 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7084	100 μL

Catalog No. 50-198-7084 Supplier Bioss Supplier No. BS6150R

Description

Rabbit Polyclonal Antibody

Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

Specifications

• Antigen: GPR124
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ADGRA2
• Gene Accession No.: Q96PE1
• Gene Alias: 8430414O08Rik; 9530074E10Rik; Adgra2; Adgra3; Adhesion G protein-coupled receptor A2; adhesion G protein-coupled receptor A3; DKFZp434C211; DKFZp434J0911; FLJ14390; G protein-coupled receptor 124; Gpr124; G-protein coupled receptor 124; KIAA1531; LOC100363275; mKIAA1531; Tem5; Tumor endothelial marker 5
• Gene Symbols: ADGRA2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human GPR124.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 25960
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG