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Invitrogen™ GPR125 Polyclonal Antibody
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Catalog No. PIPA5120377
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100 μL
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PIPA5120377 100 μL
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Catalog No. PIPA5120377 Supplier Invitrogen™ Supplier No. PA5120377
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse liver. The target is usually found in the following locations: Membrane, Multi-pass membrane protein. Immunogen sequence: ITAYLQCTRN THGSGIYPGN PQDERKAWRR CDRGGFWADD DYSRCQYAND VTRVLYMFNQ MPLNLTNAVA TARQLLAYTV EAANFSDKMD VIFVAEMIEK FGRFTKEEKS KELGDVMVDI ASNIMLADER VLWLAQREAK ACSRIVQCLQ RIATYRLAGG AHVYSTYSPN IALEAYVIKS TGFTGMTCTV FQKVAASDRT GLSDYGRRDP EGNLDKQLSF KCNVSNTFSS L.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and the LN-TM7 subfamily. Considered a novel orphan adhesion-type G-protein-coupled receptor, GPR125 has five leucine rich repeats (LRR), an immunoglobulin (Ig) domain and a GPS domain. GPR125 may play a functional role in choroidal and hippocampal response to brain injury. It is also suggested that GPR125 may be a marker for spermatogonial stem cells. Four isoforms of GPR125 exists due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR125
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene ADGRA3
Gene Accession No. Q7TT36
Gene Alias 3830613O22Rik; Adgra2; ADGRA3; adhesion G protein-coupled receptor A2; adhesion G protein-coupled receptor A3; AU044632; G protein-coupled receptor 125; Gpr125; G-protein coupled receptor 125; PGR21; probable G-protein coupled receptor 125; TEM5L; Tem5-like; UNQ556/PRO1113
Gene Symbols ADGRA3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 370-600 of human ADGRA3 (NP_660333.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 305408, 70693
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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