Invitrogen™ GPR132 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102085

Catalog No. PIPA5102085

Description

Antibody detects endogenous levels of total GPR132.

GPCR G2A is a G-protein linked receptor for lysophosphatidylcholine (LPC). It may play a role as a sensor of LPC levels at sites of inflammation to limit tissue-infiltrating-cells and progression to overt autoimmune disease and functions at the G2/M checkpoint to delay mitosis. It also may serve as a mechanism for T and B cells, and other cell types, to slow their proliferation and repair damaged DNA. It is highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus, but weakly expressed in heart and lung. In atherosclerotic plaques, expression was observed around the lipid core and at the shoulder region. It is induced by DNA-damaging agents.

Specifications

• Antigen: GPR132
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GPR132
• Gene Alias: G protein-coupled receptor 132; G protein-coupled receptor G2A; G2 accumulation protein; G2a; GPR132; MGC99642; Probable G-protein coupled receptor 132
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29933
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9UNW8
• Gene Symbols: GPR132
• Immunogen: A synthesized peptide derived from human GPR132(Accession Q9UNW8), corresponding to amino acid residues V292-R342.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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